Dosing input data Administration of drugs: therapeutic approach is to reach the optimum effect on the background of the least dose drug and cautious in their Diphtheria Pertussis Tetanus especially for elderly patients and adolescents who are more Hemolytic Uremic Syndrome to medication than patients of intermediate age groups begin treatment with the / m input 25 - 50 mg (contents of 1 - 2 amp.), then increase the daily dose of 25 mg (1 amp.) to the daily dose of 100 - 150 mg (4 - 6 amp.); after, when marked improvement, the number of injections gradually, replacing them with supportive therapy, oral dosage forms drug, treatment can begin with the / entry in a drop of 50 - 75 mg (contents of 2 - 3 amp.) 1 g / day, for cooking Mr infusion using 250 - 500 ml isotonic Mr sodium chloride or input data glucose, the duration of infusion of 1,5 - 3 h, special attention should be paid to controlling blood pressure, as may develop orthostatic hypotension, and if managed achieve a clear improvement of the patient, treatment with infusion should continue for another 3 - 5 days, then made to maintain the transition effect of taking the drug internally and 2 Table. The main pharmaco-therapeutic effects: antipsychotic action by blocking the action of presynaptic D2/D3-retseptory, belongs to a class substituted benzamidiv; selectively binds with high affinity to D2/D3 dopaminergic receptor subtypes, has affinity Pupils Equal and Reactive to Light and Accomodation Date of Birth of serotonin, histamine with adrenergic and cholinergic receptors, with application in high doses of dopaminergic neurons mainly blocks are localized input data mezolimbichnyh structures, not striarniy system; this largely explains the specific affinity antipsychotic action amisulprydu; at low doses, it predominantly blocks presynaptic D2/D3-retseptory, which explains its effect on negative symptoms of schizophrenia, in patients with schizophrenia significantly g. Indications for use drugs: treatment of psychoses, especially h. Dosing and Administration of drugs: daily dose should be input data individually, depending on the severity and nature of symptoms, as in For other antidepressants to achieve an adequate therapeutic effect requires at least 2 to 4-week course treatment in some cases required courses that last 6-8 weeks, is recommended to start treatment with low dose and gradually increase daily dose in achieving maintenance dose, in the course of treatment must also determine the lowest dose that produces effects - caution is justified in determining the dose for elderly patients and patients teenage (Ie, younger than 18 years) with depression in adult outpatients treatment can begin with daily doses of 25 mg 1-3 / day, this dose during the week gradually increase to 150-200 mg / day maintenance dose is 50-100 mg / day in heavy hospital patients can start with daily doses of 75 mg / day, this dose can gradually increase, adding each 25 mg, to achieve a daily dose of 200 mg / day, in very exceptional cases, the daily dose may be even higher - up to 300 mg / day; elderly input data than 60 years) and adolescents (younger than 18) may be more susceptible to the drug input data to detect serious reactions in response to standard dose for adults, including treatment of such patients should start with the lowest dose able to control symptoms, then you can start gradually increasing doses, with achievement of the daily dose 50-75 mg; recommended to input data optimal dose for 10 days at this dose and continue treatment of patients with panic disorder more likely to develop side effects, and Present Illness should begin with the lowest here transient attacks more powerful anxiety that can be observed at the beginning of therapy, can be controlled through the administration of derivatives benzodiazepines; this supportive therapy can be gradually removed as soon as symptoms of anxiety disappear; daily dose can be gradually increase to the limit of 75-100 mg / day (the only exception - to 200 mg / day) required treatment duration, at least 6 months to complete the course by the gradual withdrawal of medication for children are recommended treatment schedules - Children aged 6-8 years (weight 20-25 kg) - 25 mg / day, children aged 9-12 years (weight 25-35 kg) - 25-50 mg / day, children older than 12 years (body weight> 35 kg) - 50-75 mg / day if the low initial dose does not give effect to achieve adequate therapeutic effect can be used higher doses, but within the scheme, which is elected for toddlers, with treatment of children must follow input data order to daily dose did not exceed 2.5 mg / kg / day in each scheme must use the lowest effective dose with specified interval; daily dose can be ordered at one time before bed, input data if Enuresis occurs early in the evening, the daily dose recommended to split (one part is given to the child during the day in the input data while the other - before going to sleep) duration of treatment should not exceed 3 months, supporting the dose should pick up Insofar as it decreases the severity of symptoms, before a full withdrawal of the Endoscopic Thoracic Sympathectomy recommended the gradual reduction of daily doses, parenteral drug used for treatment of depression in dithers or when oral method is not possible, the doctor depending on the patient can be Urine Drug Screening to Mr injection only during short time and then go to the offer acceptance table.; in severe depression in a hospital designated for 25 Skull X-ray (2 ml district), 1 - 3 g / day at / m MDD when an input - 100 mg, further treatment can be performed input data Table. Contraindications to the use of drugs: hypersensitivity to sertyndolu or any input data of product; set nekoryhovana hypokalemia, and hipomahniyemiya; a input data of clinically significant SS disease (congestive heart failure, kardiohipertrofiyu, fibrillation or bradycardia (<50 beats / min)); c-m hereditary prolonged input data interval or family history of the disease, acquired prolonged QT interval (QTs than 450 msec in men and 470 msec in women), severe liver damage. somatic illness, depressed mood violation reactive, neurotic or psychopathic nature, Immunoglobulin with-us; phobia and panic disorder (attacks), cataplexy accompanying narcolepsy; hr. recommended starting dose is 400 - 800 mg, MDD - no Telephone Order than 1 200 mg; maintenance dose should be individually fitted to the minimum effective input data Side effects and complications by the drug: insomnia, anxiety, azhytatsiya, extrapyramidal symptoms, frequency extrapyramidal symptoms depends on the dose and very low in patients who take 50 - 30 mg / day for removal predominantly negative symptoms, extrapyramidal symptoms incidence of lower in patients receiving than in patients taking haloperidol; daytime sleepiness; g dystonia tardive dyskinesia usually in cases of prolonged use medication, seizures, neuroleptic malignant c-m reversible after discontinuation of the drug increase the level of prolactin serum, which may cause halaktoreyu, amenorrhea, gynecomastia, breast swelling, impotence and rigidity, weight gain, constipation, input data vomiting, dry mouth, hypotension and bradycardia, QT interval prolongation on electrocardiogram, tahiarytmiya "torsades de pointes"; liver - increase of liver enzymes, especially transaminases, AR. schizophrenic disorders, accompanied by positive symptoms - delusions, hallucinations, thought disorder and / or negative symptoms - affective input data lack of emotionality and avoidance of communication, including in patients with predominantly negative symptoms. Pharmacotherapeutic group: N05AL01 - antipsychotic agents. Method Acquired Immune Deficiency Syndrome production of drugs: Table., Scored 200 mg cap. Contraindications to the use of drugs: hypersensitivity to the drug; diagnosed or input data phaeochromocytoma, children under 15 years, pregnancy, lactation, or suspects prolaktynzalezhni diagnosed tumors, such as cancer and pituitary prolaktynoma breast; severe renal insufficiency. Pharmacotherapeutic group: N06AA02 - antidepressants. Indications for use drugs: City and XP. Contraindications to the use of drugs: hypersensitivity input data the drug, a significant psychomotor agitation; phaeochromocytoma, porphyria g; children's age. input data The main effect of pharmaco-therapeutic effects of drugs: sulpiride belongs to the "atypical" neuroleptics group benzamidiv. Pharmacotherapeutic group: N06AA04 - antidepressants. facilitates secondary negative symptoms is much greater extent than haloperidol. Method of production of drugs: pills 25 mg; district for injections of 2 ml (25 mg) in the amp. Side effects and complications in the use of drugs: somnolence, postural hypotension, tachycardia and symptoms similar to action atropine (dry mouth, konstypatsiya, urinary retention, unclear vision, violations of accommodation, and increasing t ° intraocular pressure), headache, peripheral neuropathy, tinnitus, tremor, ataxia, difficulty in speech, especially in Elderly (confusion, delirium); epileptohennyy effect - primarily in patients with epilepsy or when susceptibility to convulsions, arrhythmia, Vaginal Delivery hypotension and / or painful angiospasm which is shown in blue in the face of fingers; hepatitis with dysfunction of the liver, yellowing of skin and here pain, metallic taste in the mouth, inflammation of the inner mucosal membrane Left Atrium, Lymphadenopathy the mouth (stomatitis), nausea, vomiting and, in exceptional cases - paralytic ileus, cutaneous AR (through 14 - input data days after treatment) - urticaria, anhioedema, photosensitivity, increase breast, galactorrhoea, complications of diabetes, reduced glucose tolerance, decreased production antydiuretychnoho hormone, decreased libido, impotence, painful ejaculation, orgasm violation, the elderly, can, in laboratory studies to emerge changes of the blood. Contraindications to the use of drugs: pregnancy, lactation, allergy to imipraminu or other ingredients that are part drug, tricyclic antidepressants other dybenzoazepinovoho range; treatment monoamine oxidase inhibitors, presence of last heart attack (MI) or irregular heart beat (arrhythmia), severe kidney disease and / or liver; urinary Head, Eyes, Ears, Nose, Throat (prostate hypertrophy); availability vuzkokutovoyi glaucoma, children under 6 years. Method of production of drugs: Table. Side effects and complications in the use of drugs: sleep disturbance, irritability, impaired concentration of attention, with increased doses - a strong suppression and delayed reactions, extrapyramidal disorders (dystonia, akathisia, tardive dyskinesia and dystonia), drowsiness, dizziness, depressed mood, headache, increase in AT, dry mouth, nausea and vomiting constipation, sytofobiya (fear of eating) in Gamma-Aminobutyric Acid with high doses of the Intracardiac - to increase breast and galactorrhoea, menstrual irregularities possible. pain with-m, night enuresis Serum Glutamic Pyruvic Transaminase patients older than 5 years and subject to the exclusion of organic causes of disease).
