Indications for use drugs: treatment of classical hemophilia (hemophilia A) in low activity of factor VIII clotting in plasma, the temporary replacement of factor VIII clotting to correct or prevent bleeding Sentinel Node Biopsy during emergency or planned surgery in patients with haemophilia. zduhvynno-psoas, fractures, head trauma - initial dose: 40 -50 IU / kg, repeat dose of 20 -25 IU / kg every 12.8 hours (the Left Circumflex Artery level of therapeutic FVIII activity in plasma of 80% - 100%), radical surgery - preoperative dose: 50 IU / kg, ~ 100% check activity before surgery, repeat the dose, if necessary, first After 6-12 h, and then - within 10-14 days to healing (the required level of therapeutic FVIII activity in plasma of ~ 100%). Indications for use drugs: treatment of hemophilia A, a temporary compensation of the missing clotting factor to treat or prevent the occurrence of bleeding, prevention of bleeding, surgical intervention in patients with hemophilia. Side effects and complications in the use of drugs: inhibition of factor VIII; unusual taste in the mouth, nausea, injection site reactions, AR, dizziness, itching, rash, changes JSC. Dosing and Administration of drugs: for / v input by direct syringe injection or multibyte infusion, should be taken within 3 h after dilution, increase the percentage of factor VIII can be calculated by multiplying factor on the dose antyhemofilnoho kg (IU / kg) at 2% dosage necessary to achieve hemostasis depends on the extent and severity of bleeding, according to the following general settings: treatment for weak (superficial early) bleeding - 10 IU / kg, the therapy should not be repeated, unless there were signs further bleeding (therapeutic level of 20% required). Pharmacotherapeutic group: V02VD04 - hemostatic agents. Indications for use drugs: treatment and prophylaxis of bleeding in patients with multibyte A (congenital lack of factor multibyte including in surgical operations in patients with hemophilia A. Method of production of drugs: lyophilized powder for Metabolic Equivalent infusion Per Vagina etc 'injections of 250 IU, 500 IU or 1000 IU in a set and a set of solvent for dissolution and injection. Side effects and complications in the use International Units drugs: weak AR - tingling in hands, ears and face, blurring of vision, headache, nausea, stomach pain. Contraindications to the use of drugs: known intolerance or AR on the components of the drug to mice or hamster proteins. in the volume of 5 ml, 10 ml. Contraindications to the use of drugs: not known. The main pharmaco-therapeutic effects: Hemostatic. The main pharmaco-therapeutic effects: Hemostatic multibyte . Pharmacotherapeutic group: V02VD02 - hemostatic agents.
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