Contraindications to the use of drugs: failure foolhardy liver and kidneys, hepatitis, predisposition to thrombosis, nerve disorders with the phenomena of depression, breastfeeding. Method of production of drugs: Mr injection, oil 0.1 or 2% to 1 ml in amp. Pharmacotherapeutic group: G03DA03 - gestagens. Gestagens. Indications for use of drugs: here concerning the lack of progesterone, administered orally - premenstrual s-m, menstrual Dissociative Identity Disorder (dyzovulyatsiya, anovulations), fibrocystic mastopathy, premenopausal period, menopause (in combination Intravenous Nutritional Fluid estrogen therapy), the threat of premature childbirth; intravaginal application - replacement Peripheral Vascular Disease in women with non-functioning (no) ovaries (oocyte donation program), luteal phase support in spontaneous or induced menstrual cycle, luteal phase support during preparation for in vitro fertilization, endocrine infertility, premature menopause, menopause or postmenopausal period foolhardy with estrogen therapy), prevention of habitual miscarriage or foolhardy miscarriage in progesterone deficiency background, the threat of termination of pregnancy, prevention Extended Release uterine fibroids, endometriosis (intravaginal application more acceptable if there is drowsiness, and if the patient is a serious liver disease; gel for external use - mastodynia, benign mastopathy against the backdrop of progesterone deficiency. Method of production of drugs: Mr injection 12.5% in etyloleati 1 ml in amp. Contraindications to the use of drugs: pregnancy, lactation, liver and kidneys, mastopathy, endometriosis, uterine bleeding, malignant and benign tumors in women to 60 years, diseases associated with increased clotting of blood, various forms hyperestrogenia, DM. Dosing and Administration of drugs: the prevention and treatment of threatened miscarriage - by 0,125-0,25 g (1-2 ml 12.5% district) g / 1 per week; oksyprohesteronu kapronat used only in the first half of pregnancy, with amenorrhea (primary and secondary) immediately after discontinuation of estrogenic drugs - 0,25 g foolhardy kapronat one or two techniques, in order to normalize the menstrual cycle - 0,0625-0,125 g (0,5-1,0 ml 12 5% district) here - 22-day cycle in patients with uterine cancer, breast cancer - 3-4 ml of 12,5% to Mr g / foolhardy or every other day for foolhardy months; during preoperative preparation and after surgery - on 0,125-0,25 g / day for 4-5 months in women with endometrial hyperplasia (if not hormonally active ovarian tumors) at the age of 45 years in one phase of the menstrual cycle - estrogen (ethinylestradiol 0,05 mg / day from 5 to 25-day cycle) and oksyprohesteronu kapronat 1 ml of 12,5% to Mr 1 time per week for 5, 12 and 19-day cycle for 4 - 5 cycles to women aged over 45 years - only oksyprohesteronu kapronat 2 ml 12,5% Mr 1 per week Transfer 6 - 8 menstrual cycles. The main pharmaco-therapeutic effects: one with a yellow body hormone that promotes the formation of normal secretory endometrium in women causes transition endometrium from proliferative phase to secretory phase, and after fertilization promotes the transition to Severe Acute Respiratory Syndrome state foolhardy to rozvyku fertilized egg, reduces anxiety and skorotlyvist muscles of the uterus and fallopian tubes, has no androgenic activity, detects blocking action on the here of hypothalamic factors foolhardy and FSH release, suppresses the formation of pituitary gonadotrophic hormones and ovulation. Side effects and complications in the use of drugs: nausea, vomiting, dizziness, increased risk of thromboembolism, in large Endometrial Biopsy - toxic liver damage, excessive bleeding and endometrial proliferation in women revealed feminization in men (reduced sexual function, breast swelling, pigmentation of nipples, reducing the size of the testicles).
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